Effects of Thymus kotschyanus var. glabrescens Boiss. extract on mitomycin-C induced chromosomal aberrations and sister chromatid exchanges in human lymphocytes
نویسندگان
چکیده
منابع مشابه
G2 chromosomal radiosensitivity and background frequency of sister chromatid exchanges of peripheral blood lymphocytes of breast cancer patients
Background: Chromosomal alterations play an important role in carcinogenesis. Enhanced chromosomal radiosensitivity is shown for many cancer predisposition conditions including breast cancer. In this study chromosomal radiosensitivity and the frequency of background sister chromnatid exchanges (SCE) in lymphocytes of normal individuals and breast cancer patients was compared. Materials...
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Piperine is a major pungent substance and active component of black pepper (Piper nigrum Linn.) and long pepper (Piper longum Linn.). Regarding the variable biological activities of piperine, it is important to study its antimutagenic activity in somatic and germ cells in vivo. Swiss albino male mice were orally administered piperine at the doses of 5, 10 and 15mg/kg b. wt. for three consecutiv...
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The chelating agent, diethylenetriaminepentaacetic acid (DTPA) is a non-registered drug used in the treatment of over-exposure to heavy metals such as iron, zinc and lead (Fahey et al., 1961; Brugsch et al., 1965). DTPA has also been used on a few occasions in the United Kingdom when individuals have inhaled plutonium dust or received contaminated wounds (Schofield and Dolphin, 1974). These pat...
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The potential mutagenicity of fluroxene was investigated by the sister chromatid exchange (SCE) test using lymphocytes in peripheral blood from patients before and after anaesthesia. Twenty-five female patients, aged 21 -77 yr (median 36.5yr) were anaesthetized for gynaecological operations with fluroxene in nitrous oxide for 60-220 nun (median 110 min). The number of SCE per cell was the same ...
متن کاملSister chromatid exchanges in human lymphocytes treated with silica.
The abilities of Min U Sil quartz or tridymite particles to induce sister chromatid exchanges (SCEs) in cultures of human lymphocytes plus monocytes or of human purified lymphocytes were investigated. With cultures of lymphocytes plus monocytes the level of SCEs was significantly enhanced after treatment with tridymite at the highest dose tested (50 micrograms/cm2). No effect was observed with ...
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ژورنال
عنوان ژورنال: Cytotechnology
سال: 2006
ISSN: 0920-9069,1573-0778
DOI: 10.1007/s10616-006-9015-6